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Coke, Blow, Snow, Skiing, ❄️, ⛷️
Stimulant
Cocaine produces its effects by blocking the receptors responsible for the reuptake of the neurotransmitter dopamine, thus increasing the level of dopamine in the synaptic cleft. The increase in dopamine primarily in the limbic system, the area of the brain that deals with pleasure and motivation, causes the characteristic effects. [1]
As a cousin of lidocaine, cocaine can be used in medical settings as a topical anesthetic with vasoconstricting properties [2]. There are currently no therapeutic indications for cocaine that is systemically absorbed.
Oral
Intranasally “Snorting or Bump”
Intravenous (IV)
"Upper
Creates a euphoric sensation, increases alertness, provides a sense of well-being, reduces need for sleep and rest
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[1] Nestler EJ. The neurobiology of cocaine addiction. Sci Pract Perspect. 2005;3(1):4-10.
[2] Middleton RM, Kirkpatrick MB. Clinical Use of Cocaine. Drug Safety. 1993;9(3):212-217.